HRID943105

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID8028

Tetrahydrofuran

C4H8O

HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID79341

Piperidin-4-ol

C5H11NO

结构：O=C(O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21

HCID10319016

未命名化合物

PRODUCTS

生成物

结构：O=C(NC1Cc2ccccc2N(CC(=O)N2CCC(O)CC2)C1=O)c1cc2cc(Cl)sc2[nH]1

HCID10096946

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2ac32cc08de04ab89e7bc9baac879cf9
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[C:8](=[O:9])([OH:10])[CH2:11][N:12]1[C:13](=[O:34])[CH:14]([NH:22][C:23](=[O:24])[c:25]2[cH:26][c:27]3[c:28]([nH:29]2)[s:30][c:31]([Cl:33])[cH:32]3)[CH2:15][c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]21.[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH3:35][CH2:36][N:37]=[C:38]=[N:39][CH2:40][CH2:41][CH2:42][N:43]([CH3:44])[CH3:45].[CH3:51][N:52]([CH3:53])[c:54]1[cH:55][cH:56][n:57][cH:58][cH:59]1.[O:46]=[CH:47][N:48]([CH3:49])[CH3:50].[OH2:65].[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[CH2:11][N:12]2[C:13](=[O:34])[CH:14]([NH:22][C:23](=[O:24])[c:25]3[cH:26][c:27]4[c:28]([nH:29]3)[s:30][c:31]([Cl:33])[cH:32]4)[CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]32)[CH2:6][CH2:7]1