Ethanol → 4-(2-Methoxyphenyl)piperidine

HRID 98201Notes

Reaction equation

HRID 98201 reaction equation
[Al+3:33].[C:11]([O:12][CH2:13][CH3:14])(=[O:15])[CH2:16][C:17]([CH3:18])=[O:19].[CH2:20]1[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]1.[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:1][O:2][c:3]1[c:4]([CH:5]=[O:6])[cH:7][cH:8][cH:9][cH:10]1.[CH3:26][C:27]([CH3:28])([O-:29])[CH3:30].[CH3:53][CH2:54][OH:55].[H-:32].[H-:35].[H-:36].[H-:37].[K+:31].[Li+:34].[NH:38]1[CH2:39][CH2:40][CH2:41][C:42](=[O:43])[C:44]1=[O:45].[Na+:47].[OH-:46]>>[CH3:1][O:2][c:3]1[c:4]([CH:5]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[cH:7][cH:8][cH:9][cH:10]1

Participants

14

Reactant 13

HCID 702EthanolHCID 813Potassium CationHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 8082PiperidineHCID 86582-MethoxybenzaldehydeHCID 8868Ethyl AcetoacetateHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 45749132-Methylpropan-2-olateHCID 5163733Piperidine-2,3-dione

Product 1

HCID 5447384-(2-Methoxyphenyl)piperidine

Sources & evidence

ORD record
ord-212cc50f2fe5421486319387a4edfa5c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…