Dimethylformamide → 3-Benzyl-4-oxo-6-(2-trimethylsilylethynyl)-3,4-dihydroquinazoline
Reaction equation
[CH2:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[n:21]1[cH:22][n:23][c:24]2[cH:25][cH:26][c:27]([Br:32])[cH:28][c:29]2[c:30]1=[O:31].[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[CH:6].[CH3:77][N:78]([CH3:79])[CH:80]=[O:81].[CH3:7][CH2:8][N:9]([CH2:10][CH3:11])[CH2:12][CH3:13].[Cu:33]([I:34])[I:35].[Pd:36]([Cl:37])[Cl:38].[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1.[c:58]1([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[cH:72][cH:73][cH:74][cH:75][cH:76]1>>[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][c:27]1[cH:26][cH:25][c:24]2[n:23][cH:22][n:21]([CH2:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[c:30](=[O:31])[c:29]2[cH:28]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-509692e7842a44538f3df020f81508aa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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