Hydrochloric Acid → Hydrochloric Acid

HRID 136802

Reaction equation

HRID 136802 reaction equation
[Br:45][c:46]1[cH:47][s:48][cH:49][cH:50]1.[C:20]([CH3:21])([CH3:22])([CH3:23])[NH:24][c:25]1[c:26](-[c:34]2[s:35][c:36]([C:39]#[C:40][Si:41]([CH3:42])([CH3:43])[CH3:44])[cH:37][cH:38]2)[n:27][c:28]2[n:29]1[cH:30][cH:31][n:32][cH:33]2.[C:69](=[O:70])([O-:71])[O-:72].[CH2:52]([N+:53]([CH2:54][CH2:55][CH2:56][CH3:57])([CH2:58][CH2:59][CH2:60][CH3:61])[CH2:62][CH2:63][CH2:64][CH3:65])[CH2:66][CH2:67][CH3:68].[CH2:77]([N+:78]([CH2:79][CH2:80][CH2:81][CH3:82])([CH2:83][CH2:84][CH2:85][CH3:86])[CH2:87][CH2:88][CH2:89][CH3:90])[CH2:91][CH2:92][CH3:93].[CH2:99]1[O:100][CH2:101][CH2:102][CH2:103]1.[ClH:75].[Cu:104][I:105].[F-:51].[I-:76].[Na+:73].[Na+:74].[O:94]=[CH:95][N:96]([CH3:97])[CH3:98].[Pd:106]([Cl:107])[Cl:108].[c:109]1([P:110]([c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)[c:117]2[cH:118][cH:119][cH:120][cH:121][cH:122]2)[cH:123][cH:124][cH:125][cH:126][cH:127]1.[c:128]1([P:129]([c:130]2[cH:131][cH:132][cH:133][cH:134][cH:135]2)[c:136]2[cH:137][cH:138][cH:139][cH:140][cH:141]2)[cH:142][cH:143][cH:144][cH:145][cH:146]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[C:20]([CH3:21])([CH3:22])([CH3:23])[NH:24][c:25]1[c:26](-[c:34]2[s:35][c:36]([C:39]#[C:40][c:46]3[cH:47][s:48][cH:49][cH:50]3)[cH:37][cH:38]2)[n:27][c:28]2[n:29]1[cH:30][cH:31][n:32][cH:33]2.[ClH:75]

Participants

15

Reactant 13

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 11776Triphenylphosphine3×HCID 133833-BromothiopheneHCID 16028Tetrabutylammonium2×HCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 30165Iodide IonHCID 69322358Tert-butyl-[2-(5-trimethylsilanylethynyl-thiophen-2-yl)-imidazo[1,2-a]pyrazin-3-yl]-amine

Product 2

HCID 313Hydrochloric AcidHCID 69322640N-tert-butyl-2-[5-(2-thiophen-3-ylethynyl)thiophen-2-yl]imidazo[1,2-a]pyrazin-3-amine

Sources & evidence

ORD record
ord-899f9805abe6491ca23452c8ce21445f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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