Chloride → 5-Fluoro-3-((trimethylsilyl)ethynyl)pyridin-2-amine
Reaction equation
[C:10](#[CH:11])[Si:12]([CH3:13])([CH3:14])[CH3:15].[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[Cl-:17].[Cl:33][Pd:34][Cl:35].[Cl:36][CH2:37][Cl:38].[Cu:30]([I:31])[I:32].[F:1][c:2]1[cH:3][c:4]([I:9])[c:5]([NH2:8])[n:6][cH:7]1.[Li+:16]>>[F:1][c:2]1[cH:3][c:4]([C:11]#[C:10][Si:12]([CH3:13])([CH3:14])[CH3:15])[c:5]([NH2:8])[n:6][cH:7]1Participants
10
Sources & evidence
- ORD record
- ord-0154ac15f0c145ca8af3f9b3facd85d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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