Hydrochloric Acid → (2-Bromopyridin-3-yl)-(2-chlorophenyl)methanone

HRID 290570

Reaction equation

HRID 290570 reaction equation
[Br:13][c:14]1[cH:15][cH:16][cH:17][cH:18][n:19]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:54][S:55]([CH3:56])=[O:57].[CH3:58][CH2:59][O:60][C:61](=[O:62])[CH3:63].[CH:29]([N:30]([CH2:31][CH3:32])[CH:33]([CH3:34])[CH3:35])([CH3:36])[CH3:37].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[Cl:20][c:21]1[c:22]([CH:23]=[O:24])[cH:25][cH:26][cH:27][cH:28]1.[ClH:48].[S:44](=[O:45])(=[O:46])=[O:47].[n:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[Br:13][c:14]1[c:15]([C:23]([c:22]2[c:21]([Cl:20])[cH:28][cH:27][cH:26][cH:25]2)=[O:24])[cH:16][cH:17][cH:18][n:19]1

Participants

12

Reactant 11

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 1049PyridineHCID 69962-ChlorobenzaldehydeHCID 7912DiisopropylamineHCID 79732-BromopyridineHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 24682Sulfur trioxideHCID 81531DiisopropylethylamineHCID 178418339Butyllithium

Product 1

HCID 85882881(2-Bromopyridin-3-yl)-(2-chlorophenyl)methanone

Sources & evidence

ORD record
ord-abe171d042014a51b3a2254ab153ce70
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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