Tetrahydrofuran → HCID 11200574, compound

HRID 1216776Notes

Reaction equation

HRID 1216776 reaction equation
[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH3:25][Si:26]([CH3:27])([CH3:28])[C:29]#[CH:30].[CH3:50][CH2:51][N:52]([CH2:53][CH3:54])[CH2:55][CH3:56].[CH3:62][CH2:63][O:64][C:65]([CH3:66])=[O:67].[Cu:68]([I:69])[I:70].[NH2:1][CH:2]1[CH2:3][N:4]([c:8]2[n:9]([CH2:16][c:17]3[c:18]([C:19]#[N:20])[cH:21][cH:22][cH:23][cH:24]3)[c:10](=[O:15])[c:11]([Br:14])[cH:12][n:13]2)[CH2:5][CH2:6][CH2:7]1.[c:31]1([P:32]([c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46][cH:47][cH:48][cH:49]1>>[NH2:1][CH:2]1[CH2:3][N:4]([c:8]2[n:9]([CH2:16][c:17]3[c:18]([C:19]#[N:20])[cH:21][cH:22][cH:23][cH:24]3)[c:10](=[O:15])[c:11]([C:30]#[C:29][Si:26]([CH3:25])([CH3:27])[CH3:28])[cH:12][n:13]2)[CH2:5][CH2:6][CH2:7]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 66111TrimethylsilylacetyleneHCID 83717Copper iodideHCID 68622921HCID 68622921, compound

Product 1

HCID 11200574HCID 11200574, compound

Sources & evidence

ORD record
ord-89f0e920d774415ca1c4668f51cc6b46
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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