Chloride → 1-(4-Methoxy-phenyl)-6-(2'-methylaminomethyl-biphenyl-4-yl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c)pyridine-3-carboxylic acid ethyl ester

HRID 149027Notes

Reaction equation

HRID 149027 reaction equation
[C:46](#[N:47])[BH3-:48].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:39][NH2:40].[CH3:50][OH:51].[CH3:52][CH2:53][O:54][C:55]([CH3:56])=[O:57].[CH:1](=[O:2])[c:3]1[c:4](-[c:9]2[cH:10][cH:11][c:12]([N:15]3[C:16](=[O:37])[c:17]4[c:18]([c:21]([C:32](=[O:33])[O:34][CH2:35][CH3:36])[n:22][n:23]4-[c:24]4[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]4)[CH2:19][CH2:20]3)[cH:13][cH:14]2)[cH:5][cH:6][cH:7][cH:8]1.[Cl-:58].[Cl-:60].[ClH:38].[Na+:49].[Zn+2:59]>>[CH2:1]([c:3]1[c:4](-[c:9]2[cH:10][cH:11][c:12]([N:15]3[C:16](=[O:37])[c:17]4[c:18]([c:21]([C:32](=[O:33])[O:34][CH2:35][CH3:36])[n:22][n:23]4-[c:24]4[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]4)[CH2:19][CH2:20]3)[cH:13][cH:14]2)[cH:5][cH:6][cH:7][cH:8]1)[NH:47][CH3:46]

Participants

11

Reactant 10

HCID 312Chloride2×HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 6329MethylamineHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 32051Zinc(2+)HCID 498716Cyano-borohydrideHCID 223185346-(2'-Formyl-biphenyl-4-yl)-1-(4-methoxy-phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

Product 1

HCID 223185241-(4-Methoxy-phenyl)-6-(2'-methylaminomethyl-biphenyl-4-yl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c)pyridine-3-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-94252e1da5a54582beff129af7a72907
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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