Hydrochloric Acid → 6-methyl-N-tetrahydro-2H-pyran-4-yl-1H-indazole-5-carboxamide

HRID 2124497Notes

Reaction equation

HRID 2124497 reaction equation
[CH2:27]([N:28]=[C:29]=[N:30][CH2:31][CH2:32][CH2:33][N:34]([CH3:35])[CH3:36])[CH3:37].[CH3:38][c:39]1[c:40]([C:48](=[O:49])[OH:50])[cH:41][c:42]2[cH:43][n:44][nH:45][c:46]2[cH:47]1.[CH3:56][N:57]([CH3:58])[CH:59]=[O:60].[CH3:61][CH2:62][O:63][C:64](=[O:65])[CH3:66].[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[ClH:1].[ClH:26].[Na+:51].[O:2]1[CH2:3][CH2:4][CH:5]([NH2:8])[CH2:6][CH2:7]1.[OH:16][n:17]1[c:18]2[cH:19][cH:20][cH:21][cH:22][c:23]2[n:24][n:25]1.[OH:52][C:53](=[O:54])[O-:55]>>[O:2]1[CH2:3][CH2:4][CH:5]([NH:8][C:48]([c:40]2[c:39]([CH3:38])[cH:47][c:46]3[c:42]([cH:41]2)[cH:43][n:44][nH:45]3)=[O:49])[CH2:6][CH2:7]1

Participants

11

Reactant 10

HCID 313Hydrochloric Acid2×HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 4192234-AminotetrahydropyranHCID 229340406-methyl-1H-indazole-5-carboxylic acid

Product 1

HCID 694301826-methyl-N-tetrahydro-2H-pyran-4-yl-1H-indazole-5-carboxamide

Sources & evidence

ORD record
ord-67042694a7c04979a42eeb366749ed92
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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