Chloride → 5-Fluoro-3-((trimethylsilyl)ethynyl)pyridin-2-amine
Reaction equation
[C:1](#[CH:2])[Si:3]([CH3:4])([CH3:5])[CH3:6].[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[Cl-:8].[Cu:30]([I:31])[I:32].[F:16][c:17]1[cH:18][c:19]([I:24])[c:20]([NH2:23])[n:21][cH:22]1.[Li+:7]>>[C:1](#[C:2][c:19]1[cH:18][c:17]([F:16])[cH:22][n:21][c:20]1[NH2:23])[Si:3]([CH3:4])([CH3:5])[CH3:6]Participants
8
Sources & evidence
- ORD record
- ord-33c77362d3e64f918525742e805a4c0e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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