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HRID74979

反应详情

EQUATION

反应方程式

HRID 74979 的结构方程式

REACTANTS

反应物

9
结构：c1c[nH]cn1
HCID795

Imidazole

C3H4N2

结构：CO
HCID887

Methanol

CH4O

结构：[Cl-].[NH4+]
HCID25517

未命名化合物

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(P(c3ccccc3)c3ccccc3)ccc3ccccc23)cc1
HCID634876

2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

C44H32P2

结构：CCCC[N+](CCCC)(CCCC)CCCC.[F-]
HCID2724141

Tetra-n-butylammonium fluoride

C16H36FN

结构：[CH3][Al]([CH3])[CH3]
HCID16682925

Aluminum, trimethyl-

C3H9Al

结构：Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(Cl)cnc32)cc1
HCID57597747

5-Chloro-1-(4-methylbenzene-1-sulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

C20H22BClN2O4S

2 次

结构：Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(S(C)=O)n3)c3cc(Cl)cnc32)cc1
HCID67285321

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CS(=O)(=O)CC1(O)CCCCC1Nc1nc(-c2c[nH]c3ncc(Cl)cc23)ncc1F
HCID86762731

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

6
结构：CN(C)c1ccncc1
催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

2 次

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

AlMe3, [Rh2(cod)2Cl2], (S)-BINAP, THF, 0° C.; (b) TBSCl, imidazole, DMAP, DMF; (c) 3-chloroperoxybenzoic acid, CH2Cl2; (d) sodium azide, NH4Cl, MeOH, H2Ol; (e) H2, Pd—C (10%), EtOAc; (f) 5-chloro-3-(5-fluoro-4-(methylsulfinyl)pyrimidin-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine, iPr2NEt, microwave, 70° C.; (g) TBAF, THF