HRID823604

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID962

Water

H2O

HCID6228

Dimethylformamide

C3H7NO

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

HCID65578

Ethanedioyl dichloride

C2Cl2O2

HCID419223

4-Aminotetrahydropyran

C5H11NO

HCID69055516

未命名化合物

PRODUCTS

产物

HCID69054540

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-74d912e75bfe4aaaafa08be0f0f57069
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[C:34]([Cl:35])(=[O:36])[C:37]([Cl:38])=[O:39].[CH2:55]1[O:56][CH2:57][CH2:58][CH2:59]1.[CH3:48][CH2:49][N:50]([CH2:51][CH3:52])[CH2:53][CH3:54].[ClH:40].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([n:9]2[c:10]([CH:22]=[CH:23][C:24](=[O:25])[OH:26])[c:11]([C:20]#[N:21])[c:12]3[c:13]2[n:14][c:15]([CH3:19])[cH:16][c:17]3[CH3:18])[c:27]2[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]2)[cH:6][cH:7]1.[O:41]1[CH2:42][CH2:43][CH:44]([NH2:47])[CH2:45][CH2:46]1.[O:61]=[CH:62][N:63]([CH3:64])[CH3:65].[OH2:60]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([n:9]2[c:10]([CH:22]=[CH:23][C:24](=[O:25])[NH:47][CH:44]3[CH2:43][CH2:42][O:41][CH2:46][CH2:45]3)[c:11]([C:20]#[N:21])[c:12]3[c:13]2[n:14][c:15]([CH3:19])[cH:16][c:17]3[CH3:18])[c:27]2[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]2)[cH:6][cH:7]1